Active Pharmaceutical ingredients (APIS) are biologically active components found in a wide array of medications. They are synthesized in laboratories and due to the strict quality requirements of such products, they require strict particle size control. Particle size of APIs can affect solubility of the product and product integrity is of the utmost importance. Sieving and classifying APIs on a conventional screener, while commonplace, is a painstaking task due to the fine particle size of the powder and its moisture sensitivity. Furthermore, the processing must be done in a way that ensure only the highest product integrity making many screen cleaning devices like balls and sliders unusable. For finer separations, ultrasonic sieving machines may be employed, but these systems struggle at finer meshes and result in low efficiencies and have a very high operating cost associated with them.